一位足不出户、20年来几乎从不与人交往的50岁老妇收到一个奇怪包裹,包裹里是一个纸盒,纸盒里装满粗盐,粗盐里埋着两只刚割下来的人耳朵,而且,显然,这两只耳朵还不是一对……天哪!谁干的?Sherlock Holmes is asked by Susan Cushing if he could attempt to locate her sister, Mary Browner, recently married to a seaman, Jim Browner. She's worried that something may have happened to her and refuses to accept that she may have run off with another man. Holmes isn't interested in the case and offers to refer her to a missing persons agency. He is drawn into a case by Scotland Yard when the same Susan Cushing who sought to engage him receives two human ears in a box. Susan is convinced that they were sent by a lodger, a medical student whom she recently evicted for dallying with another sister, Sarah. There's now been a falling out between those sisters and Sarah is running a local mission house. Holmes isn't so sure that the ears were sent by the medical student and as he looks more deeply into the case, determines there is a connection between that occurrence and the third missing sister, Mary.
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